Effects of the iron chelator deferiprone and the T-type calcium channel blocker efonidipine on cardiac function and Ca2+ regulation in iron-overloaded thalassemic mice

Article ID	Journal	Published Year	Pages	File Type
8463347	Cell Calcium	2018	8 Pages	PDF

Keywords

Deferiprone NCX TdT RyR NTBI LTCC DFP Efonidipine HRV ICa,L ROS [Ca2+]i Adenosine Triphosphate ATP Calcium-induced calcium release left ventricle Fraction shortening Sarcoplasmic reticulum normal diet Non-transferrin bound iron SERCA Sodium-calcium exchanger Calcium regulation heart rate variability wild-type Iron overload Cardiomyopathy L-type calcium channel T-type calcium channel ejection fraction Intracellular calcium CICR Reactive oxygen species Ryanodine receptor

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology

Preview

Effects of the iron chelator deferiprone and the T-type calcium channel blocker efonidipine on cardiac function and Ca2+ regulation in iron-overloaded thalassemic mice

Authors

Juthamas Khamseekaew, Sirinart Kumfu, Siripong Palee, Suwakon Wongjaikam, Somdet Srichairatanakool, Suthat Fucharoen, Siriporn C. Chattipakorn, Nipon Chattipakorn,