| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8463932 | Cellular Immunology | 2012 | 8 Pages |
Abstract
⺠Inhibiting ROCK suppressed IL-1-stimulated secretion and mRNA levels for Caco-2 cell CXCL8 and IEC-6 cell CCL2 responses. ⺠Suppressing ROCK inhibited IL-1-induced JNK phosphorylation, but had no significant effect on IKK or IκBα responses. ⺠Suggests a role for ROCK in IL-1-stimulated JNK signaling, but not IKK/IκBα signaling, in intestinal epithelial cells.
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Authors
Brian J. Rafferty, Benjamin L. Unger, Aaron C. Perey, Steven P. Tammariello, Savvas Pavlides, Dennis W. McGee,