Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8463938 | Cellular Immunology | 2012 | 5 Pages |
Abstract
⺠HIV-1 gp120 represses IFN-γ secretion and cytotoxicity of the NK cell line NK-92MI. ⺠IL-11 activates STAT-3 in NK-92MI cells. ⺠Activation of STAT-3 by IL-11 stimulates NK-92MI IFN-γ and Bcl-XL production. ⺠IL-11 restores IFN-γ production and cytotoxicity to gp120-impaired NK-92MI cells.
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Authors
Sheena E. Favors, Lindsay M. Curd, Randal K. Gregg,