Article ID Journal Published Year Pages File Type
8463938 Cellular Immunology 2012 5 Pages PDF
Abstract
► HIV-1 gp120 represses IFN-γ secretion and cytotoxicity of the NK cell line NK-92MI. ► IL-11 activates STAT-3 in NK-92MI cells. ► Activation of STAT-3 by IL-11 stimulates NK-92MI IFN-γ and Bcl-XL production. ► IL-11 restores IFN-γ production and cytotoxicity to gp120-impaired NK-92MI cells.
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