| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8463958 | Cellular Immunology | 2012 | 8 Pages |
Abstract
⺠Polycytostatic treatment results in suppression of tumor growth in mice. ⺠Human DNA preparation significantly enhances anticancer effects of cytostatic drugs. ⺠Co-treatment with human DNA and cytostatics activates dendritic cell maturation. ⺠DNA-activated mature dendritic cells induce development of adaptive immunity. ⺠Combined therapy increases the number of CD8+/perforin+ T cells in peripheral blood.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Ekaterina A. Alyamkina, Olga Y. Leplina, Alexandr A. Ostanin, Elena R. Chernykh, Valeriy P. Nikolin, Nelly A. Popova, Anastasia S. Proskurina, Tatiana S. Gvozdeva, Evgenia V. Dolgova, Konstantin E. Orishchenko, Vladimir A. Rogachev, Sergey V. Sidorov,