| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8463970 | Cellular Immunology | 2012 | 9 Pages |
Abstract
⺠The IP-10/CXCL10 gene expression in macrophages was suppressed by a parasite. ⺠The parasite-secreted products suppressed LPS-induced IFN-β gene expression. ⺠The parasite-secreted products inhibit LPS- or IFN-γ-induced ISRE-binding activity. ⺠NF-κB RelA (p65)-dependent transcriptional activity was suppressed by the products.
Keywords
ISREIFN-stimulated gene factor 3IFN-α/β receptorTNFIFN-γ-inducible protein 10IP-10/CXCL10Spirometra erinaceieuropaeiT helperISGF3IFNGRIRFLPSIFNARElectrophoretic mobility shift assaySTATParasitic helminthinterferonIFNthymidine kinaseexcretory/secretoryEMSA یا electrophoretic mobility shift assay interferon regulatory factornuclear factorIFN-stimulated response elementtumor necrosis factornuclear factor-κBlipopolysaccharideSignal transducer and activator of transcriptionSignal transductionChemokineGasIFN-γ receptor
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Authors
Soji Fukumoto, Miki Hiroi, Paramasari Dirgahayu, Kazutoyo Miura, Sayuri Tademoto, Hitoshi Otsuki, Yoshihiro Ohmori,