Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8463999 | Cellular Immunology | 2012 | 8 Pages |
Abstract
⺠Untreated SLE patients were examined before & after steroid ± chloroquine treatment. ⺠All patients had elevated circulating DNA which notably decreased after treatment. ⺠Serum IL-10 and BAFF levels in untreated patients decreased after treatment. ⺠BAFF level in PBMC culture was not altered by chloroquine but correlated with SLEDAI. ⺠Chloroquine abolished CpG-induced B cell activation and IL-10 release in culture.
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Authors
Alma-Martina Cepika, Dragica Soldo JureÅ¡a, Jadranka MoroviÄ Vergles, Branko Malenica, Maja Å antak, Sanja KapitanoviÄ, Miroslav Mayer, Branimir AniÄ, Mirna SentiÄ, Alenka Gagro,