Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8464029 | Cellular Immunology | 2011 | 11 Pages |
Abstract
⺠T lymphocytes from mammary tumor-bearing mice express CCL2, CCL5 and CXCL2. ⺠Chemokine receptors CCR-1, -2, -3 and CXCR2 are upregulated in T lymphocytes of tumor-bearing mice. ⺠Both splenic T cells and tumor-infiltrating T lymphocytes express CCL2 and CCL5 as well as CCR1. ⺠CCL2 induces the expression of CCL2 in an autocrine manner. ⺠CCL2 induces expression of CCL5 and CXCL2 in a paracrine manner.
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Authors
Jennifer L. Owen, Michael F. Criscitiello, Stephania Libreros, Ramon Garcia-Areas, Kathleen Guthrie, Marta Torroella-Kouri, Vijaya Iragavarapu-Charyulu,