Article ID Journal Published Year Pages File Type
8464029 Cellular Immunology 2011 11 Pages PDF
Abstract
► T lymphocytes from mammary tumor-bearing mice express CCL2, CCL5 and CXCL2. ► Chemokine receptors CCR-1, -2, -3 and CXCR2 are upregulated in T lymphocytes of tumor-bearing mice. ► Both splenic T cells and tumor-infiltrating T lymphocytes express CCL2 and CCL5 as well as CCR1. ► CCL2 induces the expression of CCL2 in an autocrine manner. ► CCL2 induces expression of CCL5 and CXCL2 in a paracrine manner.
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