| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8464039 | Cellular Immunology | 2011 | 10 Pages |
Abstract
⺠MSC source influences their TLR and cytokine expression profile and their functional properties. ⺠WJ-MSC do not express TLR4 and express a nonfunctional TLR3. ⺠Inflammation upregulates TLR3 in all three MSC types and TLR4 only in BM-MSC. ⺠TLR ligation increases the production of inflammatory cytokines in AT and BM-MSC but not in WJ-MSC. ⺠The immunosuppressive potential of WJ-MSC was affected neither by inflammation nor by TLR triggering.
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Authors
Gordana Raicevic, Mehdi Najar, Basile Stamatopoulos, Cecile De Bruyn, Nathalie Meuleman, Dominique Bron, Michel Toungouz, Laurence Lagneaux,