Article ID Journal Published Year Pages File Type
8464697 Current Opinion in Cell Biology 2018 6 Pages PDF
Abstract
The large display of body shapes and sizes observed among vertebrates ultimately represent variations of a common basic body plan. This likely results from the use of homologous developmental schemes, just differentially tinkered both in amplitude and timing by natural selection. In this review, we will revisit, discuss and combine old ideas with new concepts to update our view on how the vertebrate body is built. Recent advances, particularly at the molecular level, will guide our deconstruction of the individual developmental modules that sequentially produce head, neck, trunk and tail structures, and the transitions between them.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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