| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8465061 | Current Opinion in Cell Biology | 2016 | 7 Pages |
Abstract
Unresolved chronic inflammation is implicated in all stages of cancer development and an inflammatory tumor microenvironment is considered a hallmark of cancer. Signaling pathways involved in normal tissue regeneration and repair are dysregulated both in chronic inflammation and cancer. Here, we review some of the recently identified signaling cascades and unexpected functions of stromal cells that affect both tissue regeneration and tumorigenesis in colon and pancreatic cancer, which may pave the way for the development of novel therapeutic strategies.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Marina Pesic, Florian R Greten,