Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8465268 | Current Opinion in Cell Biology | 2016 | 8 Pages |
Abstract
- Cell adhesion to the extracellular matrix (ECM) is vital for multicellular life.
- Complexes of structural and signalling proteins link the ECM to the cytoskeleton.
- Adhesion signalling networks are complex, diverse, dynamic and tightly regulated.
- Some adhesion proteins perform unexpected functions away from cell-matrix contacts.
- Nuclear roles for adhesion proteins have been revealed in diseases such as cancer.
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Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Adam Byron, Margaret C Frame,