Article ID Journal Published Year Pages File Type
8465410 Current Opinion in Cell Biology 2015 7 Pages PDF
Abstract

- The pluripotent state has a unique cell cycle relative to somatic cells.
- Extensive reciprocal crosstalk exists to maintain both pluripotency and a rapid cell cycle.
- Unique cell cycle maintains pluripotency by inhibiting differentiation.
- iPS cell reprogramming re-establishes the unique cell cycle of ES cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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