Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8465410 | Current Opinion in Cell Biology | 2015 | 7 Pages |
Abstract
- The pluripotent state has a unique cell cycle relative to somatic cells.
- Extensive reciprocal crosstalk exists to maintain both pluripotency and a rapid cell cycle.
- Unique cell cycle maintains pluripotency by inhibiting differentiation.
- iPS cell reprogramming re-establishes the unique cell cycle of ES cells.
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Authors
Michael S Kareta, Julien Sage, Marius Wernig,