Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8465637 | Current Opinion in Cell Biology | 2015 | 7 Pages |
Abstract
In the recent years there has been a tremendous increase in our understanding of chromatin, transcription and the importance of metabolites in their regulation. This review highlights what is currently sparse information that suggest existence of a refined system integrating metabolic and chromatin control. We indicate possible regulatory modes, such as feed forward amplification, that may help effect and stabilize long-lasting phenotypic decisions within and even across generations using adipogenesis as the primary context.
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Authors
Anita Ãst, John Andrew Pospisilik,