Article ID Journal Published Year Pages File Type
8465812 Current Opinion in Cell Biology 2014 6 Pages PDF
Abstract
Focal adhesion assembly and maturation often occurs concomitantly with changes in force generated within the cytoskeleton or extracellular matrix. To coordinate focal adhesion dynamics with force, it has been suggested that focal adhesion dynamics are mechanosensitive. This review discusses current understanding of the regulation of focal adhesion assembly and force transmission, and the limits to which we can consider focal adhesion plaques as mechanosensitive entities.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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