Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8466577 | Cytotherapy | 2018 | 11 Pages |
Abstract
A flow cytometry-based assay of MSCs post-IFN-γ exposure measuring expression of intracellular protein IDO-1 and cell surface protein PD-L1 captures two mechanisms of suppression and offers the potential of a relevant, rapid assay for MSC-mediated immune suppression that would fit with the manufacturing process.
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Authors
Qingdong Guan, Yun Li, Tanner Shpiruk, Swaroop Bhagwat, Donna A. Wall,