Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8466579 | Cytotherapy | 2018 | 10 Pages |
Abstract
Our findings indicate that functional OCT expression in UC-MSCs is a biological prerequisite that facilitates the intracellular uptake of metformin to induce an osteogenic effect. Future pre-clinical studies are warranted to investigate whether the expression of functional OCTs may serve as a potential biomarker to predict osteogenic responses to metformin.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Faisal E. Al Jofi, Tao Ma, Dong Guo, Monica P. Schneider, Yan Shu, Hockin H.K. Xu, Abraham Schneider,