| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8466952 | Cytotherapy | 2018 | 13 Pages |
Abstract
- IM implantation represents a minimally invasive alternative to IV infusion that supports extended survival of MSCs.
- Adult and neo-natal human MSCs can survive 5 months at an IM implantation site, but survive only 1-4 weeks when delivered IV, IP or SC.
- Equivalent cell survival is observed for 3 days after IV, IP, SC or IM transplantation.
- Survival potential can be recovered after cryopreservation, but diminishes with in vitro passage.
Keywords
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Authors
Lorena R. Braid, Catherine A. Wood, Danielle M. Wiese, Barry N. Ford,