Article ID Journal Published Year Pages File Type
8468098 Developmental Biology 2011 16 Pages PDF
Abstract
► For in vivo tests of cis-regulatory region, various experimental shortcuts have been found. ► Cross-species conservation reduces the search space. ► Long-range effects and promoter interactions can complicate the identification. ► Cell culture essays might be of limited use for developmental enhancers. ► Sequence predictions enrich but are not generic enough for most developing tissues.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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