| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8468111 | Developmental Biology | 2011 | 10 Pages |
Abstract
⺠In this study we have cloned and analyzed the expression pattern of Xenopus TRPM7. ⺠We show TRPM7 regulates convergent extension movements during gastrulation. ⺠The TRPM7 channel but not kinase domain is required for its role in gastrulation. ⺠We show that TRPM7 regulates gastrulation via its ability to passage Mg2+ ions. ⺠We show that TRPM7 regulates Rac and not Rho activation levels for gastrulation.
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Authors
Wei Liu, Li-Ting Su, Deepak K. Khadka, Courtney Mezzacappa, Yuko Komiya, Akira Sato, Raymond Habas, Loren W. Runnels,