Article ID Journal Published Year Pages File Type
8468114 Developmental Biology 2011 12 Pages PDF
Abstract
►The C. elegans P granule component GLH-1 binds to DCR-1 via pull-down analysis. ►DCR-1 localizes to the cytoplasm and at the nucleus of germ cells in the gonad. ►DCR-1 appears to be regulated by KGB-1, a Jun N-terminal kinase, for degradation. ►GLH-1 protein and mRNA levels are much reduced in the dcr-1(ok247) mutant. ►GLH-1 and DCR-1 both localize to RNP granules in stressed oocytes.
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