| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8468127 | Developmental Biology | 2011 | 12 Pages |
Abstract
⺠Sox1, Sox2 and Sox3 inhibit BMP signaling and induce neural tissue. ⺠SoxB1 proteins are not redundant but rather induce unique gene expression profiles. ⺠Oct91, the Xenopus homologue of Oct4, behaves similarly to the SoxB1s. ⺠Constitutively active Sox1 and Sox2 repress neuron formation; Sox3 causes apoptosis. ⺠The synergy in mammals between Sox2 and Oct4 is conserved in frogs.
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Authors
Tenley C. Archer, Jing Jin, Elena S. Casey,