Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8468132 | Developmental Biology | 2011 | 13 Pages |
Abstract
⺠We studied the function of the RhoU GTPase in neural crest cell migration. ⺠RhoU is expressed in migrating Xenopus CNC cells. ⺠RhoU is critical for CNC cell migration. ⺠RhoU knock-down results in defect in cell attachment, spreading and migration in vitro. ⺠The level of RhoU activity is critical for explant polarity and directional CNC cell migration in vitro.
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Authors
Philippe Fort, Linda Guémar, Emmanuel Vignal, Nathalie Morin, Cécile Notarnicola, Pascal de Santa Barbara, Sandrine Faure,