| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8468134 | Developmental Biology | 2011 | 12 Pages |
Abstract
⺠Myod and Cdkn1c (p57Kip2) interact genetically to promote myogenesis. ⺠Cdkn1c expression is Hedgehog-dependent in zebrafish adaxial cells. ⺠Cdkn1c promotes Myod protein accumulation. ⺠MRFs maintain Cdkn1c expression in vivo, thereby creating a positive feedback loop. ⺠Cdkn1c is not required for adaxial cell cycle exit, but to drive differentiation.
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Authors
Daniel P.S. Osborn, Kuoyu Li, Yaniv Hinits, Simon M. Hughes,