| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8469513 | Egyptian Journal of Medical Human Genetics | 2018 | 6 Pages |
Abstract
Based on these data, it can be concluded that the V279F polymorphism influences the surface structure, energy stability, epitope and immunogenicity of the Lp-PLA2 protein. The changes in the immunogenicity and epitope shift indicated that the protein is valuable as a biomarker for use in acute myocardial infarct. The results of this study provide an opportunity to develop monoclonal antibodies that are specifically able to identify V279F polymorphisms as a predictor of the risk of acute myocardial infarct.
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Authors
Widodo Widodo, Anggia Noor Ramadhani, Anissa Nofitasari, Sapti Puspitarini, Didik Priyandoko, Mohammad Saifur Rohman, Mifetika Lukitasari,