Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8471972 | Immuno-analyse & Biologie Spécialisée | 2006 | 4 Pages |
Abstract
Inflammation is the process by which the body responds to injury. C-reactive protein (CRP) is one of the acute phase proteins that increase during systemic inflammation. It represents thus a marker of first choice of an inflammatory phenomenon. CRP assay is however also carried out in another field. Laboratory evidence and findings from clinical studies showed that inflammation plays a part in atherosclerosis'etiology (arterial sclerosis characterized by the accumulation of amorphous lipids in the internal tunic of the vessel). Thus CRP represents, even at lower rates than in acute inflammation, a marker of the cardiovascular risk; indeed an individual with high basal CRP has an increased cardiovascular risk. A high sensitivity assay for CRP test (hs-CRP) is thus needed.
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Authors
F. Grandjean, V. Berlage, L. Auger, F. Robert, P. Vankerkhoven, J.-M. Cirriez,