Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8472126 | Immunobiology | 2017 | 8 Pages |
Abstract
MMPs-2/9 and TIMP-2 are both involved in the biology of IH and the propranolol pathways enabling their antiangiogenic properties. The most reliable method of IH examination appears to be direct MMPs-2/9 mRNA evaluation in tumor tissue; and MMP-2 evaluation in patients' serum is a valuable complement to it. Tissue and serum mRNA MMPs assessment may represent a suitable novel biomarker identifying tumor progression and involution processes with potential clinical impact in IH as well as in cancer disease.
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Authors
Katarzyna Taran, Aneta WnÄk, Józef Kobos, Ewa Andrzejewska, PrzemysÅaw Przewratil,