Article ID Journal Published Year Pages File Type
8472991 Journal of Molecular Biology 2012 11 Pages PDF
Abstract
► smFRET results suggest that the unfolded state is collapsed at low denaturant. ► SAXS suggests that the low- and high-denaturant unfolded states are indistinguishable. ► Poor overlap between the data sets has historically obscured the significance of this discrepancy. ► Parallel studies on one protein under one set of conditions confirm the discrepancy.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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