Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8472991 | Journal of Molecular Biology | 2012 | 11 Pages |
Abstract
⺠smFRET results suggest that the unfolded state is collapsed at low denaturant. ⺠SAXS suggests that the low- and high-denaturant unfolded states are indistinguishable. ⺠Poor overlap between the data sets has historically obscured the significance of this discrepancy. ⺠Parallel studies on one protein under one set of conditions confirm the discrepancy.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Tae Yeon Yoo, Steve P. Meisburger, James Hinshaw, Lois Pollack, Gilad Haran, Tobin R. Sosnick, Kevin Plaxco,