Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8473097 | Journal of Molecular and Cellular Cardiology | 2018 | 32 Pages |
Abstract
Our results indicate that activation of PAR-1 contributes to Dox-induced cardiotoxicity. Inhibition of PAR-1 may be a new approach to reduce Dox-induced cardiotoxicity in cancer patients.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Silvio Antoniak, Kohei Tatsumi, Clare M. Schmedes, Steven P. Grover, Rafal Pawlinski, Nigel Mackman,