Modelling the pathogenesis of Myotonic Dystrophy type 1 cardiac phenotype through human iPSC-derived cardiomyocytes

Article ID	Journal	Published Year	Pages	File Type
8473431	Journal of Molecular and Cellular Cardiology	2018	43 Pages	PDF

Keywords

APD MLC2v ACTN2 hiPSC-CMs Myotonic Dystrophy type 1 (DM1)MBNL1 CUGBP1 KSR DMPK TnnT2 DADS MyHC HDFs DM1 AFM hiPSCs Electrophysiological analysis SCD MEF CMS FFT INa Ventricular tachycardia Fast Fourier transform sodium current Potassium current embryoid body α-Myosin heavy chain Human induced pluripotent stem cells Human induced pluripotent stem cell-derived cardiomyocytes Human dermal fibroblasts Ventricular fibrillation Cardiomyocytes Action potential duration Sudden cardiac death mouse embryonic fibroblast atomic force microscopy Myotonic dystrophy type 1 wild type action potential

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology

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Modelling the pathogenesis of Myotonic Dystrophy type 1 cardiac phenotype through human iPSC-derived cardiomyocytes

Authors

Paola Spitalieri, Rosa V. Talarico, Silvia Caioli, Michela Murdocca, Annalucia Serafino, Marco Girasole, Simone Dinarelli, Giovanni Longo, Sabina Pucci, Annalisa Botta, Giuseppe Novelli, Cristina Zona, Ruggiero Mango, Federica Sangiuolo,