Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes

Article ID	Journal	Published Year	Pages	File Type
8473458	Journal of Molecular and Cellular Cardiology	2018	65 Pages	PDF

Keywords

ECC InsP3 cardiac myosin binding protein-C cMyBP-c FCR NHE ET-1 PLC NCX PKC Na+/Ca2+ exchanger Na+/H+ exchanger Ca2+-induced Ca2+ release endothelin endothelin-1 ISO isoproterenol Excitation-contraction coupling diacylglycerol Sarcoplasmic reticulum DAG phospholipase C SERCA Cardiac myocyte adult rat ventricular myocytes Chelerythrine CICR

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology

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Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes

Authors

Ioannis Smyrnias, Normann Goodwin, Dagmar Wachten, Jonas Skogestad, Jan Magnus Aronsen, Emma L. Robinson, Kateryna Demydenko, Anne Segonds-Pichon, David Oxley, Sakthivel Sadayappan, Karin Sipido, Martin D. Bootman, H. Llewelyn Roderick,