| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8473804 | Journal of Molecular and Cellular Cardiology | 2016 | 10 Pages |
Abstract
Experimentally-calibrated populations of human AP models identify ICaL re-activation as the key mechanism for repolarisation abnormalities in HCM, and combined INCX, INaL and ICaL block as effective anti-arrhythmic therapies also able to partially reverse the HCM electrophysiological phenotype.
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Authors
Elisa Passini, Ana Mincholé, Raffaele Coppini, Elisabetta Cerbai, Blanca Rodriguez, Stefano Severi, Alfonso Bueno-Orovio,