Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib

Article ID	Journal	Published Year	Pages	File Type
8473862	Journal of Molecular and Cellular Cardiology	2016	44 Pages	PDF

Keywords

HGFR lentiviral RTK HFpEF TIMP1 uPA HGF ERK1,2 HCM ChF tPA CTRL PAI1 DOX ECM tissue inhibitor of metalloproteinases-1 cardiovascular disease doxycycline CVD Hepatocyte growth factor Transcription factor Tissue-type plasminogen activator urokinase-type plasminogen activator Extracellular matrix Plasminogen activator inhibitor-1 congestive heart failure heart failure Cardiac hypertrophy Hypertrophic cardiomyopathy Control Receptor Tyrosine Kinase Met receptor

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology

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Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib

Authors

Valentina Sala, Simona Gallo, Stefano Gatti, Enzo Medico, Elisa Vigna, Daniela Cantarella, Lara Fontani, Massimo Natale, James Cimino, Mara Morello, Paolo Maria Comoglio, Antonio Ponzetto, Tiziana Crepaldi,