Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8474049 | Journal of Molecular and Cellular Cardiology | 2015 | 10 Pages |
Abstract
ZFP580 promotes not only the differentiation of EPCs into ECs by increasing the expression of eNOS and the availability of nitric oxide, but also the vessel formation in vitro and in vivo. This might represent a novel mechanism of ZFP580 in EPC differentiation and its therapeutic value in the treatment of vascular disease.
Keywords
Dil-Ac-LDLFACSMNCsVCAM-1S-nitroso-N-acetylpenicillamineC2H2bFGFHRPVEGFR-2EPCsMEPKruppel-like transcription factorKLFUEA-IeNOSECsl-NAMEl-NG-Nitroarginine methyl esterq-PCRDifferentiationtumor necrosis factor-αfluorescence-activated cell sortingEndothelial progenitor cellsEndothelial cellsMononuclear cellsendothelial nitric oxide synthaseSNAPVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)TNF-αvascular cell adhesion molecule-1quantitative real-time polymerase chain reactionHorseradish peroxidase (HRP)Vascular endothelial growth factor receptor-2
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Authors
Shuping Wei, Jiawen Huang, Yuming Li, Juan Zhao, Yuyu Luo, Xiangyan Meng, Huiyan Sun, Xin Zhou, Mei Zhang, Wencheng Zhang,