| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8474078 | Journal of Molecular and Cellular Cardiology | 2015 | 9 Pages |
Abstract
Utilizing an ex vivo co-cultivation approach to model key cellular and molecular events found in vivo during infarction, cardiomyocyte phagocytosis was found to be inefficient, in part due to myocyte-induced shedding of macrophage MERTK. These findings warrant future studies to identify other cofactors of macrophage-cardiomyocyte cross-talk that contribute to cardiac pathophysiology.
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Authors
Shuang Zhang, Xin-Yi Yeap, Lubov Grigoryeva, Shirley Dehn, Matthew DeBerge, Michael Tye, Emily Rostlund, Dorien Schrijvers, Zheng Jenny Zhang, Ronen Sumagin, Warren G. Tourtellotte, Daniel Lee, Jon Lomasney, John Morrow, Edward B. Thorp,