Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8474709 | Journal of Molecular and Cellular Cardiology | 2014 | 9 Pages |
Abstract
Differentially regulated genes and modulated pathways were identified that were associated with recurrent cardiovascular outcomes in first-time AMI patients. This cell-based approach for risk stratification in AMI could represent a novel, non-invasive platform to anticipate modifiable pathways and therapeutic targets to optimize long-term outcome for AMI patients and warrants further study to determine the role of metabolic remodeling and regenerative processes required for optimal outcomes.
Keywords
FGFR1cholesterylester transfer proteinTGFBRcAMP responsive element binding protein 1ACTA2VIMIL-1 betaIL1bapoA1CREB1EGFVimentinABCA1CETPLDLRpKaAmIApolipoprotein A1Pathway analysisTranscriptomeEMTBloodMicroarrayAcute myocardial infarctionepidermal growth factorFibroblast growth factor 1smooth muscle alpha-actinprotein kinase Aepithelial-to-mesenchymal transitionlow density lipoprotein receptor
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Authors
Rahul Suresh, Xing Li, Anca Chiriac, Kashish Goel, Andre Terzic, Carmen Perez-Terzic, Timothy J. Nelson,