| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8474759 | Journal of Molecular and Cellular Cardiology | 2014 | 9 Pages |
Abstract
Similar to what has been seen in adults and in a rat model of IDC, total and (18:2)4CL are lower in pediatric IDC. Unique CL species profiles are seen in heart tissue from children with IDC compared to adults. Differences in CL biosynthesis and remodeling enzyme expression likely explain the differences in CL profiles observed in IDC and implicate unique age-related mechanisms of disease.
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Authors
Kathryn C. Chatfield, Genevieve C. Sparagna, Carmen C. Sucharov, Shelley D. Miyamoto, Jonathan E. Grudis, Rebecca D. Sobus, Jamie Hijmans, Brian L. Stauffer,