| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8474808 | Journal of Molecular and Cellular Cardiology | 2014 | 8 Pages |
Abstract
Non-failing human hearts exhibit transmural heterogeneity of contractile properties. In failing organs, region-specific fibrosis produces the greatest contractile deficits in the mid-myocardium. Targeting fibrosis and sarcomeric proteins in the mid-myocardium may be particularly effective therapies for heart failure.
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Authors
Premi Haynes, Kristofer E. Nava, Benjamin A. Lawson, Charles S. Chung, Mihail I. Mitov, Stuart G. Campbell, Arnold J. Stromberg, Sakthivel Sadayappan, Mark R. Bonnell, Charles W. Hoopes, Kenneth S. Campbell,