Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475084 | Journal of Molecular and Cellular Cardiology | 2013 | 10 Pages |
Abstract
β3-AR regulates myocardial NOS activity and ROS via activation of nNOS involving reciprocal changes in phosphorylation at two regulatory sites. These data identify a novel and potent anti-oxidant and anti-hypertrophic pathway due to nNOS post-translational modification that is coupled to β3-AR receptor stimulation.
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Authors
Vabren L. Watts, Fernando M. Sepulveda, Oscar H. Cingolani, Alice S. Ho, Xiaolin Niu, Rosa Kim, Karen L. Miller, Koenraad Vandegaer, Djahida Bedja, Kathleen L. Gabrielson, Gerald Rameau, Brian O'Rourke, David A. Kass, Lili A. Barouch,