Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475099 | Journal of Molecular and Cellular Cardiology | 2013 | 9 Pages |
Abstract
The studies performed show that loss of functional TTCCs is associated with bi-nucleation and myocyte withdrawal from the cell cycle. Loss of α1G TTCCs slowed the transition from mono- to bi-nucleation and resulted in an adult heart with a greater number of small cardiac myocytes. These results suggest that TTCCs are involved in the regulation of myocyte size and the exit of myocytes from the cell cycle during the first week after birth.
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Authors
Fang Wang, Hui Gao, Hajime Kubo, Xiaoxuan Fan, Hongyu Zhang, Remus Berretta, Xiongwen Chen, Thomas Sharp, Timothy Starosta, Catherine Makarewich, Ying Li, Jeffrey D. Molkentin, Steven R. Houser,