Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475145 | Journal of Molecular and Cellular Cardiology | 2013 | 9 Pages |
Abstract
⺠Stimulation of hormone receptor activates the sarcolemmal NHE1. ⺠Activation of NHE1 leads to increase in intracellular pH and Na+ concentration. ⺠Ionic changes via NHE1 can initiate cardiac hypertrophy and heart failure. ⺠We discuss upstream and downstream signaling pathways of NHE1.
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Authors
Shigeo Wakabayashi, Takashi Hisamitsu, Tomoe Y. Nakamura,