Article ID Journal Published Year Pages File Type
8475145 Journal of Molecular and Cellular Cardiology 2013 9 Pages PDF
Abstract
► Stimulation of hormone receptor activates the sarcolemmal NHE1. ► Activation of NHE1 leads to increase in intracellular pH and Na+ concentration. ► Ionic changes via NHE1 can initiate cardiac hypertrophy and heart failure. ► We discuss upstream and downstream signaling pathways of NHE1.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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