Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475150 | Journal of Molecular and Cellular Cardiology | 2013 | 6 Pages |
Abstract
⺠NHE-1 inhibitors protect the ischemic and reperfused myocadium. ⺠Clinical trials have produced diverse results as well as evidence of adverse effects. ⺠The bases for clinical results can likely be rationalized based on various factors. ⺠NHE-1 inhibitors reduce heart failure and improve post-cardiac arrest resuscitation. ⺠Further development of NHE-1 inhibitors for cardiac therapeutics is warranted.
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Authors
Morris Karmazyn,