Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475239 | Journal of Molecular and Cellular Cardiology | 2013 | 10 Pages |
Abstract
⺠FAT10 is an ubiquitin-like protein family whose functions in the heart are unknown. ⺠FAT10 is expressed in the human and murine hearts. ⺠Ischemia and hypoxia increase expression of FAT10. ⺠FAT10 suppresses p53 and miR-34a levels but increases BCL2 level. ⺠FAT10 protects against cardiac myocyte apoptosis.
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Authors
Xiaogang Peng, Jianghua Shao, Yang Shen, Yunguo Zhou, Qing Cao, Jinzhu Hu, Wenfeng He, Xin Yu, Xiuxia Liu, Ali J. Marian, Kui Hong,