| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475247 | Journal of Molecular and Cellular Cardiology | 2013 | 12 Pages |
Abstract
⺠In CGRP knockout mice, neointimal formation after vascular injury is exacerbated. ⺠CGRP deficiency affects injury-induced proliferation of VSMCs rather than ECs. ⺠In CGRP knockout mice, oxidative stress and macrophage infiltration are increased. ⺠Bone marrow-derived cells do not contribute to the enhanced neointimal formation. ⺠CGRP significantly suppresses VSMC proliferation and migration.
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Authors
Lei Yang, Takayuki Sakurai, Akiko Kamiyoshi, Yuka Ichikawa-Shindo, Hisaka Kawate, Takahiro Yoshizawa, Teruhide Koyama, Yasuhiro Iesato, Ryuichi Uetake, Akihiro Yamauchi, Megumu Tanaka, Yuichi Toriyama, Kyoko Igarashi, Takayuki Shindo,