Article ID Journal Published Year Pages File Type
8475250 Journal of Molecular and Cellular Cardiology 2013 9 Pages PDF
Abstract
► Ivabradine treatment reduced the incidence of reperfusion ventricular arrhythmia. ► The anti-arrhythmic effects of ivabradine were due to heart rate reduction. ► Mean heart rate during ischaemia is a determinant of reperfusion arrhythmias. ► Heart rate reduction delayed onset of ischaemia-induced electrophysiological changes. ► Selective heart rate lowering is a potential anti-arrhythmic therapeutic strategy.
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