| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475255 | Journal of Molecular and Cellular Cardiology | 2013 | 9 Pages |
Abstract
⺠Preterm infants exposed to cimetidine have increased patent ductus arteriosus (PDA). ⺠Antacids that inhibit CYP enzymes relax the term and preterm mouse DA. ⺠CYP inhibition, but not H2 antagonism, alters DA tone in histamine deficient mice. ⺠Oxygen-induced DA constriction is selectively inhibited by cimetidine and famotidine.
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Authors
Robert B. Cotton, Lisa P. Shah, Stanley D. Poole, Noah J. Ehinger, Naoko Brown, Elaine L. Shelton, James C. Slaughter, H. Scott Baldwin, Bibhash C. Paria, Jeff Reese,