Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475295 | Journal of Molecular and Cellular Cardiology | 2013 | 8 Pages |
Abstract
⺠Cardiac intra-sarcoplasmic reticulum (SR) free [Ca2 +] ([Ca2 +]SR), SR Ca2 + load and Ca2 + release ⺠[Ca2 +]SR changes during E-C coupling (Ca2 + scraps), Ca2 + sparks/blinks and Ca2 + waves. ⺠Spatiotemporal [Ca2 +]SR gradients constrain intra-SR Ca2 + diffusion models. ⺠Controversies about SR Ca2 + release activation, termination and wave propagation
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Authors
Donald M. Bers, Thomas R. Shannon,