Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475315 | Journal of Molecular and Cellular Cardiology | 2013 | 9 Pages |
Abstract
⺠Mitochondria occupy a third of the cell volume of cardiac myocytes. ⺠Mitochondria have an elaborate system of calcium uptake and extrusion mechanisms. ⺠Mitochondrial Ca signaling is crucial for excitation-metabolism-contraction coupling. ⺠Mitochondria decode cytosolic Ca signals to respond to energy demands and buffer Ca. ⺠Beat-to-beat transmission or slow integration of cytosolic Ca signals are debated.
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Authors
Elena N. Dedkova, Lothar A. Blatter,