| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475319 | Journal of Molecular and Cellular Cardiology | 2013 | 9 Pages |
Abstract
⺠We model differential PKA phosphorylation kinetics of ICaL vs. IKs on transient EADs. ⺠A mismatch between ISO-induced ICaL and IKs increase is key for transient EADs. ⺠PLB dephosphorylation barely affects transient EAD1s, but reduces EAD2s. ⺠PLM phosphorylation attenuates transient EAD1s and EAD2s by different mechanisms.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Yuanfang Xie, Eleonora Grandi, Jose L. Puglisi, Daisuke Sato, Donald M. Bers,