| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475360 | Journal of Molecular and Cellular Cardiology | 2013 | 14 Pages |
Abstract
⺠Reportedly sulforaphane (SFN) prevents the experimental diabetic nephropathy. ⺠Here we demonstrated that SFN also prevented diabetic cardiomyopathy. ⺠SFN increased Nrf2 expression and transcription function in vitro and in vivo. ⺠Nrf2 siRNA prevented SFN protection from high glucose-induced changes in H9C2 cells. ⺠SFN cardioprotection from diabetes was long-sustained after the end of SFN treatment.
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Authors
Yang Bai, Wenpeng Cui, Ying Xin, Xiao Miao, Michelle T. Barati, Chi Zhang, Qiang Chen, Yi Tan, Taixing Cui, Yang Zheng, Lu Cai,