Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475367 | Journal of Molecular and Cellular Cardiology | 2013 | 10 Pages |
Abstract
⺠We studied the effects of training/detraining on the cardiomyocyte function of SHR. ⺠Hypertension resulted in deficient cardiomyocyte contractile function. ⺠Exercise improved cardiomyocyte [Ca2 +]i transient and contractile function in SHR. ⺠These benefits were related to increased PLBser16 and SERCA2a cardiac expression. ⺠Such exercise training-induced adaptations were reversed within 4 weeks of detraining.
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Authors
Miguel Araujo Carneiro-Júnior, Judson Fonseca Quintão-Júnior, Lucas Rios Drummond, Victor Neiva Lavorato, Filipe Rios Drummond, Daise Nunes Queiroz da Cunha, Marco Aurélio Amadeu, Leonardo Bonato Felix, Edilamar Menezes de Oliveira,